Cyllene Therapeutics Receives U.S. FDA Regenerative Medicine Advanced Therapy (RMAT) Designation for EG110A in Neurogenic Detrusor Overactivity (NDO)

September 14, 2026 Cyllene Therapeutics Receives U.S. FDA Regenerative Medicine Advanced Therapy (RMAT) Designation for EG110A in Neurogenic Detrusor Overactivity (NDO)
  • RMAT designation follows proof of concept demonstration of strong, lasting efficacy and good safety profile in initial NDO Phase 1b/2a trial ongoing in the US.
  • EG110A is the first non-systemic, site-specific inhibitor of CGRP+ neurons, with initial applications to treat severe bladder disorders. A single treatment course could potentially provide long-lasting symptomatic relief in patients.

Read the full press release here.

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